Is Melanotan Safe to Use?

Overview Information

Melanotan-II is a lab-made chemical that is similar to a hormone found in people. Be careful not to confuse melanotan-II with melatonin.

Melanotan-II is given as a shot to produce erections in men with ED (erectile dysfunction), tan the skin, and prevent skin cancers caused by sun exposure.

How does it work?

Melanotan-II is similar to a substance in our bodies, called “melanocyte-stimulating hormone,” which increases the production of skin-darkening pigments. Melanotan-II might also work in the brain to stimulate erections of the penis.


It is recommended that the person start the usage with 0.25 mg. If there are no serious side effects then the doctors recommend increasing the dosage by 0.25mg.


Uses & Effectiveness?

Possibly Effective for

  • Producing erections in men with ED (erectile dysfunction), when given as a shot under the skin.

Insufficient Evidence for

  • Preventing skin cancers due to sun exposure, when given as a shot under the skin.
  • Other conditions.


The side effects of using Melanotan II are as follows;


Nausea is one of the primary side effects of Melanotan II and can last up to 1 to 2 weeks. The drug intake is initially in very small quantities to make sure that the body adapts to it. The dosage is only increased when the nausea is under control or is mild. Eighty-five percent people have experienced mild nausea after the initial usage of this drug.


Facial flushing

Seventy-five percent of the people experienced facial flushing when they started using this drug. Facial flushing is referred as the feeling of warmness and sudden reddening of the face. The facial flushing usually last about 2 to 4 hours after the initial use of Melanotan II but if it persists for a longer period of time is it important to consult a doctor as soon as possible.



Forty-four percent of the people who used Melanotan II experienced fatigue. Usually, people start experiencing tiredness from the second dose onwards. It is advised that the dosage should be taken in a very small amount and even then you are getting tired it is better to take it before you go to sleep at the night.



After the initial usage of Melanotan II, most of the men have reported having become more aggressive and also their libido increased much higher. The better way for men to overcome this side effect is to work out more in the gym or jog daily. It is also found that the men who used Melanotan II have been capable of doing longer workouts.



Twenty-six percent of the people who have used this drug have experienced vomiting. Experts say that this is quite common and nothing to be worried of as the body has been injected with a foreign substance and it may take a while for the body to adapt it. But if the vomiting continues for more than 5 or 6 days, then it is better to rush to a doctor.


Injection Site Reactions

The Melanotan II is usually taken in the form of injection. Thirteen percentages of the people have experienced reactions such as allergies at the injection site. Some people have reported that they started seeing a lump at the site of injection taken and is red in color. Some people have experienced itching also. These are quite normal and should be taken seriously only if these do not disappear after a week.


Stomach cramping

A very few people have reported that they experienced stomach cramps after two to three dosages of Melanotan II. This is an uncommon side effect and is nothing to be worried about.


Uneven pigmentation

About 1 in 10 people who used Melanotan II drugs experienced uneven pigmentation or irregular darkening of the skin. This happens due to the overdosage of the drug.


Many successful cases of tanning due to Melanotan II drugs have been reported throughout the world. Even though the drug is not legally licensed or approved by FDA, it is easily available online and in medical stores. It is strictly advised to use the drug after consulting a doctor. Even though the first usage limit is restricted to 0.25mg, some bodies may not accept even that small quantity. Therefore it is essential to consult a doctor about the right dosage required and when should it be administered.

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